debilitate

1 - Half of all the astronauts on space flights are afflicted with debilitating space sickness, an ailment akin to car sickness and marked by nausea and vomiting.

2 - When given alongside radiation therapy for head and neck cancer, acupuncture has shown for the first time to reduce the debilitating side effect of xerostomia.

3 - Pain is the most common physical complaint while depression is the second most debilitating chronic medical condition.

4 - Osteoarthritis can be a debilitating condition affecting joints throughout the body.

5 - Debilitating pain in the head at night is the most common symptom of brain tumour.